![]() Initial Serum C-reactive Protein Level as a Predictor of Increasing Serum Vancomycin Concentration During Treatment.Ĭomparison of Sb2-Infliximab with Originator-Infliximab in the Measurement of Serum Concentrations A Short Communication.Īlternative Sampling Devices to Collect Dried Blood Microsamples: State-of-the-Art. Therapeutic Drug Monitoring and Pharmacokinetic Analysis of cyclosporine in a Pediatric Patient with Hemophagocytic Lymphohistiocytosis Complicated by Diabetes Insipidus: A Grand Round. ![]() Therapeutic Drug Monitoring of Psychotropics as a Diagnostic Tool for CYP2D6 Poor Metabolizer Phenotype.Įtiologies and Outcomes Associated with Tacrolimus Levels out of Typical Range that Lead to High Variability in Kidney Transplant Recipients.Ī Population Pharmacokinetic Modeling and Simulation Study of Posaconazole Oral Suspension in Immunocompromised Pediatric Patients. drug interactions: fluoxetine 20-60 mg/day may cause a two- to fourfold increase in plasma concentrations of desipramine, possibly associated with signs of toxicity including decreased energy, psychomotor retardation, sedation, dry mouth, and memory loss. ![]() Untimed Efavirenz Drug Levels After Switching From Brand to Generic Formulations: A Short Communication.Ī Loading Micafungin Dose in Critically Ill Patients Undergoing Continuous Veno-Venous Hemofiltration or Continuous Veno-Venous Hemodiafiltration: A Population Pharmacokinetic Analysis. Simultaneous Determination of Six Antiretroviral Drugs in Human Hair Using an LC-ESI+-MS/MS Method: Application to Adherence Assessment.Ĭan We Predict Individual Concentrations of Tacrolimus After Liver Transplantation? Application and Tweaking of a Published Population Pharmacokinetic Model in Clinical Practice. Tacrolimus measured in capillary volumetric microsamples in pediatric patients-a cross-validation study. as of september 19, 2019, the pennsylvania prescription drug monitoring program is sharing data with 21 other states, military health systems and d.c. In day-to-day practice, drug monitoring can be used as a critical tool to help obtain objective data about patients’ drug use, promote compliance of safe use of controlled substance, and meet certain regulatory expectations.
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After that we added more complex features: Direction auto-detection, per-paragraph direction setting, correction of Mozilla’s charset detection when it misses on right-to-left languages, etc. So, both of us started improving it, and at some point we noticed each other’s work, joined forces and merged our code. Actually, there was an earlier extension which started addressing this problem, but most of the functionality was missing. One extension was an initiative that two different people started simultaneously: Myself and Asaf Romano were both frustrated by how Thunderbird was not exposing GUI for setting the direction of email messages you were reading - so that we were reading Hebrew email laid out the wrong way. BiDi Mail UI - BiDirectional language UI and other ehhancement Also, Thunderbird is multi-platform, relatively popular, based on a layout engine with pretty good support for Right-to-Left languages (I speak Hebrew), and - most importantly - it was very extension-friendly. Not long after I first got an email address as a teenager, I was already using Netscape (which had a browser and a mail client combined) in the old days and the habit stuck. Now, Thunderbird may not be the best mail client out there in many respects and can certainly be horrible when it comes to internal project governance - but, it’s been my email client for my entire adult life. I carefully auto-filter my email, trying to make sure I don’t leave anything intended for me, or important to me unread. I’m a heavy user of email - with periods in my life in which I received dozens of messages a day. ![]() My extensions for the Thunderbird email client are the two most prominent examples of this scratch-your-own-itch kind of project. And then you spend a days, and weeks (and maybe months) working out all the corner cases, improving performance, adding feature you don’t need at all and you think are totally useless, but other users insist on having… so it takes on a life of its own. ![]() ![]() Writing a piece of software can be like scratching an itch: You’re missing functionality on a system or in an application you’re using, you find yourself repeating some tedious manual procedure, and at some point you just say “Fuck it, I’ll just automate this myself, and do it right once and for all”. 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Installing Kodi on an Amazon Fire TV If you plan on using KODI in this manner, you will want to use a VPN like IPVanish to keep yourself (37)… Install IPVanish on Firestick with Screenshots - This article will help you install the Venom Kodi Addon on your firestick device. Use IPVanish VPN with Kodi on a Firestick and access blocked content. In fact, IPVanish has the best Firestick VPN app, and is easy to set up on most IP Addresses: 40,000+Cheapest Price: $2.62/mo for 12 monthsServers: 1,400Torrenting: Unlimited Rating: 9.1/10 Īn easy to follow guide show you how you can install IPVanish on an Amazon Fire Stick. It can also unblock US Netflix, and is great for Kodi streaming. Tip: Use the IPVanish connectivity issues on Fire TV Stick 5. IPVanish Connection Issues: Solved! (2021 Guide)ĮxpressVPN is very easy to set up and is known to be hassle free and without connection issues. Go to ‘Apps’ at the top of your home screen. 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The Level of Academic and Environmental Stress among College Students: A Case in the College of Education. Academic Stress : A Case of the Undergraduate students. ACADEMIC STRESS AMONG ADOLESCENT IN RELATION TO. Stress : Definition and history Author ’ s personal copy. The study revealed that the brain gym exercise was efficient in stress reduction. Level of stress was significantly associated with gender as chi square value (12.513) at p value (.003) and education of father as chi square value (10.213) at p value (0.001) and father's profession as chi-square value (14.506) but no significant association with the other socio demographic variables. The study result demonstrated a statistically significant difference in Levels of stress pre- and post-test in the experimental group at p-value˂0.0001. Brain gym exercise was given for 15 days. Self-structured student stress scale was utilized to determine the amount of stress among the participants. Total 120 samples were choosed by using proportionate stratified random sampling techniques. An interventional study attempted to evaluate the impact of brain gym exercise on mitigating stress levels in high school pupils in a selected government high school,odisha with objectives to measure the level of stress among high school students, to evaluate the effect of brain gym exercise on mitigating the degree of stress on high school students in order to determine the relationship between stress levels and certain demographic characteristics. The ACC/AHA Task Force on Practice Guidelines (Task Force), whose charge is to develop, update, or revise practice guidelines for cardiovascular diseases and procedures, directs this effort. The American College of Cardiology (ACC) and the American Heart Association (AHA) have jointly engaged in the production of guidelines in the area of cardiovascular disease since 1980. Moreover, clinical practice guidelines can provide a foundation for other applications, such as performance measures, appropriate use criteria, and both quality improvement and clinical decision support tools. An organized and directed approach to a thorough review of evidence has resulted in the production of clinical practice guidelines that assist clinicians in selecting the best management strategy for an individual patient. When properly applied, expert analysis of available data on the benefits and risks of these therapies and procedures can improve the quality of care, optimize patient outcomes, and favorably affect costs by focusing resources on the most effective strategies. The medical profession should play a central role in evaluating the evidence related to drugs, devices, and procedures for the detection, management, and prevention of disease. Initial Clinical Evaluation in Patients With AFe76 Reviewer Relationships With Industry and Other Entities (Relevant)e68 Postoperative Cardiac and Thoracic Surgery: Recommendationse51Įvidence Gaps and Future Research Directionse52Īuthor Relationships With Industry and Other Entities (Relevant)e66 WPW and Pre-Excitation Syndromes: Recommendationse49 Hypertrophic Cardiomyopathy: Recommendationse45 Surgical Maze Procedures: Recommendationse44 Pacemakers and Implantable Cardioverter-Defibrillators for Prevention of AFe43 Outpatient Initiation of Antiarrhythmic Drug Therapye40ĪF Catheter Ablation to Maintain Sinus Rhythm: Recommendationse41 6.3.1.Ĭomplications Following AF Catheter Ablatione43 Pharmacological Agents for Preventing AF and Maintaining Sinus Rhythme35 6.2.1.Īntiarrhythmic Drugs to Maintain Sinus Rhythm: Recommendationse35 6.2.1.1. Pharmacological Cardioversion: Recommendationse33 Prevention of Thromboembolism: Recommendationse33ĭirect-Current Cardioversion: Recommendationse33 Selecting and Applying a Rate-Control Strategye31 5.3.1.Įlectrical and Pharmacological Cardioversion of AF and Atrial Fluttere33 6.1.1. Other Pharmacological Agents for Rate Controle30 ![]() Nondihydropyridine Calcium Channel Blockerse29 Specific Pharmacological Agents for Rate Controle29 5.1.1. Percutaneous Approaches to Occlude the LAAe26Ĭardiac Surgery-LAA Occlusion/Excision: Recommendatione26 Nonpharmacological Stroke Preventione26 4.4.1. Interruption and Bridging Anticoagulatione25 ![]() New Target-specific Oral Anticoagulantse22Ĭonsiderations in Selecting Anticoagulantse23 Risk Stratification Schemes (CHADS 2, CHA 2DS 2-VASc, and HAS-BLED)e17 Selecting an Antithrombotic Regimen-Balancing Risks and Benefitse17 4.1.1.1. Risk-Based Antithrombotic Therapy: Recommendationse15 4.1.1. Risk Factors and Associated Heart Diseasee13Ĭlinical Evaluation: Recommendatione14 3.1.īasic Evaluation of the Patient With AFe14 3.1.1.Ĭlinical History and Physical Examinatione14 The Renin-Angiotensin-Aldosterone Systeme13 Pathophysiological Mechanismse13 2.2.3.1. ![]() Mechanisms of AF and Pathophysiologye11 2.2.1.Įlectrophysiological Mechanismse12 2.2.2.1. Definitions and Pathophysiology of AFe8 2.1.1.Ītrial Flutter and Macroreentrant Atrial Tachycardiae9 Iago convinces Roderigo to wake Brabantio and tell him about his daughter's elopement. Iago hates Othello for promoting a younger man named Cassio above him, whom Iago considers a less capable soldier than himself, and tells Roderigo that he plans to exploit Othello for his own advantage. Roderigo is upset because he loves Desdemona and had asked her father, Brabantio, for her hand in marriage. Roderigo, a wealthy and dissolute gentleman, complains to his friend Iago, an ensign, that Iago has not told him about the secret marriage between Desdemona, the daughter of a senator named Brabantio, and Othello, a Moorish general in the Venetian army. Illustration by Percy Anderson for Costume Fanciful, Historical and Theatrical, 1906 Act I Due to its enduring themes of passion, jealousy, and race, Othello is still topical and popular and is widely performed, with numerous adaptations. ![]() Iago is Othello's malevolent ensign, who maliciously stokes his master's jealousy until the usually stoic Mute kills his beloved wife in a fit of blind rage. He has recently married Desdemona, a beautiful and wealthy Venetian lady much younger than himself, against the wishes of her father. Othello is a Moorish military commander who was serving as a general of the Venetian army in defence of Cyprus against invasion by Ottoman Turks. The story revolves around two characters, Othello and Iago. The port city of Famagusta finally fell to the Ottomans in 1571 after a protracted siege. ![]() Othello (full title: The Tragedy of Othello, the Moor of Venice) is a tragedy written by William Shakespeare, probably in 1603, set in the contemporary Ottoman–Venetian War (1570–1573) fought for the control of the Island of Cyprus, a possession of the Venetian Republic since 1489. Ira Aldridge as Othello, Henry Perronet Briggs (c. Such a detailed analysis will not be attempted here except insofar as it becomes necessary to establish the character and relationships of the first three documents in the present series. With the aid of these copies, the one at an early stage and the others at a later, it has been possible to determine the evolution of the text with more or less precision. Shortly after the adoption of the Declaration, Jefferson made copies of the “Rough draught” and sent them to distant friends, including Richard Henry Lee, Edmund Pendleton, George Wythe, Philip Mazzei, and probably John Page. The earliest and most important of these is the copy in John Adams’ handwriting, probably made before Jefferson had shown the text to Franklin but after a few minor changes had been effected (this copy is reproduced in Boyd, Declaration of Independence, together with all known texts in Jefferson's handwriting). It would be difficult if not impossible to say at what stage or by whom these various changes had been made if it were not for the fact that several contemporary copies of Jefferson's text were made. Almost all of these were indicated on the “Rough draught,” and one minorchange was made even after Congress had adopted the final text (Boyd, Declaration of Independence, 1945, p. In all there were eighty-six alterations, made at various stages by Jefferson, by Adams and Franklin, by the Committee of Five, and by Congress. Some of their suggested alterations, if not all, were made in their own handwriting on the draft that Jefferson later endorsed “original Rough draught.” The Committee itself apparently made few changes, but Congress excised about a fourth of the text, including the famous passage concerning Negro slavery. He did so, submitting it first to Adams and then to Franklin. The Committee selected Jefferson to prepare a draft. Yet the main outlines are clear and indisputable. The procedure of the Committee of Five between 11 and 28 June became the subject of some difference of opinion between Adams and Jefferson in 1823. The signing of the engrossed parchment copy took place on 2 Aug. On 19 July Congress ordered the Declaration to be engrossed and signed. The question as to whether it was signed on 4 July is discussed in the notes to Jefferson's Notes of Proceedings in the Continental Congress, 7 June to 1 Aug. Jefferson's Declaration was debated on 2-4 July and was, after considerable revision, adopted on the last day. It was for this reason, doubtless, that the Declaration as adopted on 4 July bore the title “A Declaration by the Representatives of the United States of America, in General Congress Assembled,” whereas the engrossed parchment copy of the Declaration was entitled “The Unanimous Declaration of the Thirteen United States of America.” This, however, was not a unanimous vote, since the delegates of New York were bound by their instructions and abstained from voting (they were released by the New York Convention on 9 July). Congress, sitting as a committee of the whole on 1 July, debated the Lee Resolution for nine hours without interruption this was the decisive debate but the Resolution was not put to vote by Congress until the following day, when it was adopted. The draft of the Declaration agreed upon by the Committee was reported to Congress on 28 June. On 11 June this Committee of Five was appointed, consisting of Thomas Jefferson, John Adams, Benjamin Franklin, Roger Sherman, and Robert R. Since this delay was apparently caused by the desire for unanimity and since the act of independence was a foregone conclusion, Congress decided to avoid further delay by appointing a Committee of Five to draft a declaration that would announce to the world and at the same time justify the act. ![]() ![]() On 8 and 10 June Congress considered this Resolution, and on the latter date postponed action on it to 1 July. under date) instructing its delegates in Congress to propose independence and the consequence was Richard Henry Lee's Resolution of Independence, 7 June 1776 (q.v. On the Virginia Convention unanimously adopted the Resolutions (q.v. Nevertheless, the transcendent importance of this charter of national liberties and the recent discovery of additional information respecting Jefferson's drafting of it require special presentation, though this cannot be as detailed and as comprehensive as the studies of Hazelton and others. Boyd, The Declaration of Independence: The Evolution of the Text, Princeton, 1945. ![]() ![]() A Study in the History of Political Ideas, N.Y., 19 and Julian P. Hazelton, The Declaration of Independence: Its History, N.Y., 1906 Carl Becker, The Declaration of Independence. A full analysis of the many textual changes made in the Declaration of Independence from the time it was drafted by Jefferson to the time of its final adoption by Congress has been made in the following: John H. |
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